In the context of vaccines manufactured to prevent COVID-19 pandemic, consider the following statements:
- The Serum Institute of India produced COVID-19 vaccine named Covishield using mRNA platform.
- Sputnik V vaccine is manufactured using vector-based platform.
- COVAXIN is an inactivated pathogen-based vaccine.
Which of the statements given above are correct?
(a) 1 and 2 only
(b) 2 and 3 only
(c) 1 and 3 only
(d) 1, 2 and 3
Explanation
The correct answer is (b) 2 and 3 only.
- Covishield is not an mRNA-based vaccine. It is a viral vector vaccine developed by AstraZeneca and Oxford University, and manufactured by the Serum Institute of India.
- Sputnik V is a vector-based vaccine developed by the Gamaleya Research Institute of Epidemiology and Microbiology in Russia. It uses a human adenovirus vector platform.
- COVAXIN is an inactivated pathogen-based vaccine developed by Bharat Biotech in collaboration with the Indian Council of Medical Research – National Institute of Virology.
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- Covishield is a viral vector vaccine that uses a modified chimpanzee adenovirus vector encoding the SARS-CoV-2 Spike (S) glycoprotein.
- Sputnik V is a combination vector vaccine that uses two different adenovirus vectors (Ad26 and Ad5) for the first and second doses, respectively, to provide immunity against COVID-19.
- COVAXIN is a whole-virion inactivated vaccine that stimulates the immune system to produce antibodies against the inactivated SARS-CoV-2 strain.
